6) Stephen Saad – Net Worth: $2.1 Billion

This self-made pharmaceutical tycoon’s Aspen Pharmacare is the largest producer of generic medicines in Africa. Its stock shot up 75 percent in the past year which is mainly due to booming business in Asia and Australia. His net worth increased by more than $500 million during last year.

5) Patrice Motsepe – Net Worth: $2.1 Billion

This 52-year-old self-made billionaire is South Africa’s first black billionaire. He is also the first African to sign Bill Gates and Warren Buffet’s Giving Pledge. His publicly traded mining conglomerate African Rainbow Minerals has interests in platinum, chrome, nickel, iron, coal, gold, manganese and copper.